Cortisol levels are sensed by the pituitary gland. Signals from the pituitary gland stimulate the adrenal glands' production of cortisol. The adrenal gland endocrine system includes the adrenal glands and pituitary gland. Bone loss, leading to fractures over timeĬontact your doctor if you have symptoms that suggest Cushing syndrome, especially if you're taking corticosteroid medication to treat a condition such as asthma, arthritis or inflammatory bowel disease.Other possible signs and symptoms of Cushing syndrome Signs and symptoms men with Cushing syndrome may experience Thicker or more visible body and facial hair (hirsutism).Signs and symptoms women with Cushing syndrome may experience Slow healing of cuts, insect bites and infections.Thinning, fragile skin that bruises easily.Pink or purple stretch marks (striae) on the skin of the abdomen, thighs, breasts and arms.Weight gain and fatty tissue deposits, particularly around the midsection and upper back, in the face (moon face), and between the shoulders (buffalo hump).Common signs and symptoms of Cushing syndrome The signs and symptoms of Cushing syndrome can vary depending on the levels of excess cortisol.
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